NAD+ 500mg
The coenzyme at the center of longevity research. Found in every cell, NAD+ powers the enzyme families most associated with healthy aging, DNA repair, and cellular energy — and declines significantly with age.
How It Works
The Target
Over 500 enzymatic reactions throughout the body. NAD+ is a coenzyme essential for energy metabolism, DNA repair, and cellular signaling — and it declines substantially with age.
The Mechanism
Functions as both an electron carrier (shuttling electrons in energy production pathways) and a substrate consumed by sirtuins (SIRT1-7) for gene silencing and DNA repair, PARPs for DNA damage response, and CD38 for immune signaling. When NAD+ levels drop, these repair and maintenance systems slow down.
Why It Matters
NAD+ decline is now considered a hallmark of aging. Clinical trials of NAD+ precursors (NR, NMN) have shown they can safely elevate blood NAD+ levels in humans, with ongoing research into downstream effects on metabolism, cognition, and cardiovascular function.
Specifications
| Purity | >=98% |
| MW | ~663 Da |
| Form | Lyophilized white powder |
| Storage | -20 degrees C, protect from moisture |
| Reconstitution | Sterile water (highly soluble) |
| Shelf Life | 24 months |
Published References
Read the full NAD+ research article →