MT-2 10mg
A broad-spectrum melanocortin receptor agonist with Phase 1 clinical data. Studied across multiple receptor pathways, making it a valuable research tool for understanding the full scope of the melanocortin system.
How It Works
The Target
Melanocortin receptors (MC1R through MC5R). MT-2 is a cyclic synthetic analogue of alpha-MSH with broad affinity across all five receptor subtypes.
The Mechanism
At MC1R on skin cells: triggers the cAMP/PKA cascade that activates tyrosinase, converting tyrosine into eumelanin (dark pigment). At MC3R/MC4R in the brain: activates hypothalamic circuits involved in sexual arousal and appetite regulation. The cyclic structure makes it resistant to enzymatic breakdown.
Why It Matters
MT-2 was the first compound to demonstrate that melanocortin receptor activation could simultaneously influence pigmentation and sexual function through central nervous system pathways, leading to the development of PT-141 (bremelanotide).
Specifications
| Purity | >=98% |
| MW | ~1.0 kDa |
| Form | Lyophilized white powder |
| Storage | -20 degrees C, protect from light |
| Reconstitution | Bacteriostatic water |
| Shelf Life | 24 months |
Published References
Read the research: Melanotan-2 MC1R signaling & melanogenesis pathway →