IGF-1 LR3 1mg
An extended-acting analogue of a naturally occurring growth factor, engineered for a 20-30 hour research window. One of the most referenced compounds in laboratory studies of muscle cell development and signaling.
How It Works
The Target
IGF-1 receptors throughout the body, particularly in skeletal muscle. LR3 is a modified version of natural IGF-1 with two key engineering changes.
The Mechanism
The modifications (Arg3 substitution + 13-amino acid extension) dramatically reduce binding to IGF binding proteins, which normally sequester and deactivate IGF-1. This means LR3 stays active 20-30 hours vs 20 minutes for native IGF-1. It activates the PI3K/Akt/mTOR pathway — the primary signaling cascade for protein synthesis.
Why It Matters
The extended activity window and reduced binding protein interference make LR3 one of the most studied compounds in muscle cell development and regeneration research.
Specifications
| Purity | >=98% |
| MW | ~9.1 kDa |
| Form | Lyophilized white powder |
| Storage | -20 degrees C |
| Reconstitution | Acetic acid 0.1% / PBS |
| Shelf Life | 24 months |