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Endocrine

HCG 5000iu

HCG 5000iu — research compound vial

A well-characterized glycoprotein hormone with multiple FDA-approved medical uses. Used as a standard reference compound in reproductive and endocrine research for decades, with one of the most established safety profiles in the field.

5000iu
$28

Read the research: LHCGR signaling & steroidogenesis →

How It Works

The Target

LH/hCG receptors (LHCGR) primarily on Leydig cells in the testes and granulosa cells in the ovaries. hCG is a naturally occurring glycoprotein hormone produced during pregnancy.

The Mechanism

Mimics luteinizing hormone (LH) at its receptor, triggering the same downstream cascade: Gs protein activation, cAMP production, PKA signaling, and ultimately steroidogenesis. In males, this stimulates testosterone production. In females, it triggers ovulation and supports corpus luteum function.

Why It Matters

Multiple FDA-approved medical uses with decades of clinical data. In research contexts, hCG is used to maintain intratesticular testosterone during exogenous hormone administration, preserving spermatogenesis and testicular function.

Specifications

FormLyophilized white powder
Storage2-8 degrees C; -20 degrees C long-term
ReconstitutionBacteriostatic water
Shelf Life18 months
Potency5000 IU/vial

Published References

peer
Optimal restoration of spermatogenesis after testosterone therapy using human chorionic gonadotropin and follicle-stimulating hormone (Fertility and sterility 2025) ↗
peer
Sublingual human chorionic gonadotropin as an adjuvant to ovulation induction (JBRA assisted reproduction 2024) ↗
clinical
hCG Priming in Women With Diminished Ovarian Reserve (ClinicalTrials.gov Phase 3 2026) ↗
peer
Production of Mare Chorionic Girdle Organoids That Secrete Equine Chorionic Gonadotropin (International journal of molecular sc... 2023) ↗
peer
Reading the hCG tea leaves (F&S reports 2025) ↗
peer
Gonadotropin-Releasing Hormone Agonist Versus Recombinant Human Chorionic Gonadotropin Triggering in Fertility Preservation Cycles (Reproductive sciences (Thousand Oaks,... 2021) ↗

HCG 5000iu

Third-party verified · batch COAs · US-based fulfillment

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Research Use Only. HCG 5000iu is sold exclusively for in vitro laboratory research. It is not a drug, dietary supplement, food, or medical device, and has not been evaluated by the FDA for any purpose. Not for human or veterinary use. NST Research makes no therapeutic, diagnostic, or health claims regarding any compound listed.