Catalog Research
CatalogDermal & Aging › GHK-Cu 50mg
Dermal & Aging

GHK-Cu 50mg

GHK-Cu 50mg — research compound vial

A naturally occurring copper complex your body produces less of as you age. With 50+ published studies, it is one of the most thoroughly researched compounds in skin biology and cellular renewal science.

50mg
$55

How It Works

The Target

Gene expression — specifically, over 4,000 human genes involved in tissue repair, inflammation, and cellular aging. GHK naturally occurs in human plasma but declines significantly with age.

The Mechanism

The GHK tripeptide binds copper(II) ions and activates TGF-beta signaling, which upregulates collagen, decorin, and glycosaminoglycan synthesis. It also resets the expression of genes that shift toward inflammatory and destructive patterns during aging back toward regenerative patterns.

Why It Matters

GHK-Cu is one of the few compounds shown to broadly reset age-related gene expression changes. Plasma levels drop from ~200 ng/mL at age 20 to ~80 ng/mL at age 60, correlating with declining tissue repair capacity.

Specifications

Purity>=98%
MW~340 Da (as copper complex)
FormLyophilized blue powder
Storage-20 degrees C, protect from light
ReconstitutionSterile water (produces blue solution)
Shelf Life24 months

Published References

review
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions (Journal of the American Academy of Or... 2026) ↗
review
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective (BioImpacts : BI 2025) ↗
review
Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes? (Molecules (Basel, Switzerland) 2025) ↗
peer
Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms (Frontiers in pharmacology 2025) ↗
peer
An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant (Colloids and surfaces. B, Biointerfaces 2025) ↗
peer
The glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6 (Redox biology 2024) ↗

GHK-Cu 50mg

Third-party verified · batch COAs · US-based fulfillment

View in Catalog →
Research Use Only. GHK-Cu 50mg is sold exclusively for in vitro laboratory research. It is not a drug, dietary supplement, food, or medical device, and has not been evaluated by the FDA for any purpose. Not for human or veterinary use. NST Research makes no therapeutic, diagnostic, or health claims regarding any compound listed.