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Longevity

Epitalon 10mg

Epitalon 10mg — research compound vial

A tetrapeptide with an unusually long research history — over 30 years of published science, including some of the longest longitudinal aging studies ever conducted. Studied for its relationship with the pineal gland and cellular aging.

10mg
$50

How It Works

The Target

Telomerase — the enzyme that maintains telomere length at chromosome ends. Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide based on the naturally occurring pineal gland peptide epithalamin.

The Mechanism

Activates telomerase reverse transcriptase (hTERT), enabling cells to rebuild the protective telomere caps that shorten with each division. Also influences pineal gland function, modulating melatonin production and circadian regulation through neuroendocrine pathways.

Why It Matters

Khavinson's research showed Epitalon reactivated telomerase in human somatic cells and was associated with increased lifespan in animal models. The dual telomere/pineal mechanism makes it unique among peptide bioregulators.

Specifications

Purity>=98%
MW~390 Da
FormLyophilized white powder
Storage-20 degrees C
ReconstitutionSterile water
Shelf Life24 months

Published References

review
Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties (International journal of molecular sc... 2025) ↗
review
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions (Journal of the American Academy of Or... 2026) ↗
peer
The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic Retinopathy (Stem cell reviews and reports 2025) ↗
peer
Epitalon-activated telomerase enhance bovine oocyte maturation rate and post-thawed embryo development (Life sciences 2025) ↗
review
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging (Frontiers in aging 2026) ↗
peer
Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity (Biogerontology 2025) ↗

Epitalon 10mg

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Research Use Only. Epitalon 10mg is sold exclusively for in vitro laboratory research. It is not a drug, dietary supplement, food, or medical device, and has not been evaluated by the FDA for any purpose. Not for human or veterinary use. NST Research makes no therapeutic, diagnostic, or health claims regarding any compound listed.